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lcga peptides  (Lactocore Inc)

 
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    Lactocore Inc lcga peptides
    Behavioral analyses of the anxiolytic-like properties of <t>LCGA</t> <t>tetra-peptides</t> in Danio rerio . (A,B) In the NTT, LCGA-17 (10 mg/kg) increased the time the fish spent in the upper half of the tank, similar to fluvoxamine (Flv, 5 mg/kg), indicating an anxiolytic-like response (A) . By contrast, diazepam (Diaz, 5 mg/kg) reduced the time spent in the upper half of the tank (A) . None of the treatments affected the distance traveled (B) . (C) In the LDB, LCGA-17 increased the time spent in the lit compartment, closely mimicking the anxiolytic-like effect of diazepam. (D) In the SPT, both LGCA-17 and LCGA-26 increased the time spent out of the shoaling zone, again mimicking an anxiolytic-like effect of diazepam. Neither fluvoxamine (5 mg/kg) nor LCGA-59 and LCGA-83 (10 mg/kg) affected the behavior in the LDB and SPT (B,C) . Data are presented as % of vehicle control. ∗ p < 0.05, ∗∗ p < 0.01, ∗∗∗ p ≤ 0.001, n = 18–30, Mann–Whitney, with corrections for multiple comparisons using the FDR method, at a q threshold of 0.05.
    Lcga Peptides, supplied by Lactocore Inc, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/product/lcga+peptides/pmc08372404-41-0-4?v=Lactocore+Inc
    Average 90 stars, based on 1 article reviews
    lcga peptides - by Bioz Stars, 2026-07
    90/100 stars

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    1) Product Images from "In silico Screening and Behavioral Validation of a Novel Peptide, LCGA-17, With Anxiolytic-Like Properties"

    Article Title: In silico Screening and Behavioral Validation of a Novel Peptide, LCGA-17, With Anxiolytic-Like Properties

    Journal: Frontiers in Neuroscience

    doi: 10.3389/fnins.2021.705590

    Behavioral analyses of the anxiolytic-like properties of LCGA tetra-peptides in Danio rerio . (A,B) In the NTT, LCGA-17 (10 mg/kg) increased the time the fish spent in the upper half of the tank, similar to fluvoxamine (Flv, 5 mg/kg), indicating an anxiolytic-like response (A) . By contrast, diazepam (Diaz, 5 mg/kg) reduced the time spent in the upper half of the tank (A) . None of the treatments affected the distance traveled (B) . (C) In the LDB, LCGA-17 increased the time spent in the lit compartment, closely mimicking the anxiolytic-like effect of diazepam. (D) In the SPT, both LGCA-17 and LCGA-26 increased the time spent out of the shoaling zone, again mimicking an anxiolytic-like effect of diazepam. Neither fluvoxamine (5 mg/kg) nor LCGA-59 and LCGA-83 (10 mg/kg) affected the behavior in the LDB and SPT (B,C) . Data are presented as % of vehicle control. ∗ p < 0.05, ∗∗ p < 0.01, ∗∗∗ p ≤ 0.001, n = 18–30, Mann–Whitney, with corrections for multiple comparisons using the FDR method, at a q threshold of 0.05.
    Figure Legend Snippet: Behavioral analyses of the anxiolytic-like properties of LCGA tetra-peptides in Danio rerio . (A,B) In the NTT, LCGA-17 (10 mg/kg) increased the time the fish spent in the upper half of the tank, similar to fluvoxamine (Flv, 5 mg/kg), indicating an anxiolytic-like response (A) . By contrast, diazepam (Diaz, 5 mg/kg) reduced the time spent in the upper half of the tank (A) . None of the treatments affected the distance traveled (B) . (C) In the LDB, LCGA-17 increased the time spent in the lit compartment, closely mimicking the anxiolytic-like effect of diazepam. (D) In the SPT, both LGCA-17 and LCGA-26 increased the time spent out of the shoaling zone, again mimicking an anxiolytic-like effect of diazepam. Neither fluvoxamine (5 mg/kg) nor LCGA-59 and LCGA-83 (10 mg/kg) affected the behavior in the LDB and SPT (B,C) . Data are presented as % of vehicle control. ∗ p < 0.05, ∗∗ p < 0.01, ∗∗∗ p ≤ 0.001, n = 18–30, Mann–Whitney, with corrections for multiple comparisons using the FDR method, at a q threshold of 0.05.

    Techniques Used: Control, MANN-WHITNEY



    Similar Products

    lcga peptides  (Lactocore Inc)
    90
    Lactocore Inc lcga peptides
    Behavioral analyses of the anxiolytic-like properties of <t>LCGA</t> <t>tetra-peptides</t> in Danio rerio . (A,B) In the NTT, LCGA-17 (10 mg/kg) increased the time the fish spent in the upper half of the tank, similar to fluvoxamine (Flv, 5 mg/kg), indicating an anxiolytic-like response (A) . By contrast, diazepam (Diaz, 5 mg/kg) reduced the time spent in the upper half of the tank (A) . None of the treatments affected the distance traveled (B) . (C) In the LDB, LCGA-17 increased the time spent in the lit compartment, closely mimicking the anxiolytic-like effect of diazepam. (D) In the SPT, both LGCA-17 and LCGA-26 increased the time spent out of the shoaling zone, again mimicking an anxiolytic-like effect of diazepam. Neither fluvoxamine (5 mg/kg) nor LCGA-59 and LCGA-83 (10 mg/kg) affected the behavior in the LDB and SPT (B,C) . Data are presented as % of vehicle control. ∗ p < 0.05, ∗∗ p < 0.01, ∗∗∗ p ≤ 0.001, n = 18–30, Mann–Whitney, with corrections for multiple comparisons using the FDR method, at a q threshold of 0.05.
    Lcga Peptides, supplied by Lactocore Inc, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/product/lcga+peptides/pmc08372404-41-0-4?v=Lactocore+Inc
    Average 90 stars, based on 1 article reviews
    lcga peptides - by Bioz Stars, 2026-07
    90/100 stars
    		  Buy from Supplier

    Image Search Results


    Behavioral analyses of the anxiolytic-like properties of LCGA tetra-peptides in Danio rerio . (A,B) In the NTT, LCGA-17 (10 mg/kg) increased the time the fish spent in the upper half of the tank, similar to fluvoxamine (Flv, 5 mg/kg), indicating an anxiolytic-like response (A) . By contrast, diazepam (Diaz, 5 mg/kg) reduced the time spent in the upper half of the tank (A) . None of the treatments affected the distance traveled (B) . (C) In the LDB, LCGA-17 increased the time spent in the lit compartment, closely mimicking the anxiolytic-like effect of diazepam. (D) In the SPT, both LGCA-17 and LCGA-26 increased the time spent out of the shoaling zone, again mimicking an anxiolytic-like effect of diazepam. Neither fluvoxamine (5 mg/kg) nor LCGA-59 and LCGA-83 (10 mg/kg) affected the behavior in the LDB and SPT (B,C) . Data are presented as % of vehicle control. ∗ p < 0.05, ∗∗ p < 0.01, ∗∗∗ p ≤ 0.001, n = 18–30, Mann–Whitney, with corrections for multiple comparisons using the FDR method, at a q threshold of 0.05.

    Journal: Frontiers in Neuroscience

    Article Title: In silico Screening and Behavioral Validation of a Novel Peptide, LCGA-17, With Anxiolytic-Like Properties

    doi: 10.3389/fnins.2021.705590

    Figure Lengend Snippet: Behavioral analyses of the anxiolytic-like properties of LCGA tetra-peptides in Danio rerio . (A,B) In the NTT, LCGA-17 (10 mg/kg) increased the time the fish spent in the upper half of the tank, similar to fluvoxamine (Flv, 5 mg/kg), indicating an anxiolytic-like response (A) . By contrast, diazepam (Diaz, 5 mg/kg) reduced the time spent in the upper half of the tank (A) . None of the treatments affected the distance traveled (B) . (C) In the LDB, LCGA-17 increased the time spent in the lit compartment, closely mimicking the anxiolytic-like effect of diazepam. (D) In the SPT, both LGCA-17 and LCGA-26 increased the time spent out of the shoaling zone, again mimicking an anxiolytic-like effect of diazepam. Neither fluvoxamine (5 mg/kg) nor LCGA-59 and LCGA-83 (10 mg/kg) affected the behavior in the LDB and SPT (B,C) . Data are presented as % of vehicle control. ∗ p < 0.05, ∗∗ p < 0.01, ∗∗∗ p ≤ 0.001, n = 18–30, Mann–Whitney, with corrections for multiple comparisons using the FDR method, at a q threshold of 0.05.

    Article Snippet: LCGA peptides (supplied by Lactocore, Inc., 98% purity) were administered at a dose of 1 and 10 mg/kg (i.p., prepared in saline on the day of the experiment).

    Techniques: Control, MANN-WHITNEY